Cefpodoxime Impurity 48 CAS CATO-C4X-157948
| CAS No. | CATO-C4X-157948 |
| Molecular Formula | C21H27N5O10S2 |
| Molecular Weight | 573.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefpodoxime Impurity 48 (CAS CATO-C4X-157948, C21H27N5O10S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefpodoxime Impurity 48 (C21H27N5O10S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H27N5O10S2 |
| Molecular Weight | 573.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefpodoxime Standards
- Cefpodoxime Proxetil Impurity 10 (CAS CATO-C4X-157910)
- Cefpodoxime Impurity 50 (CAS CATO-C4X-157950)
- Cefpodoxime Proxetil Impurity 9 (CAS CATO-C4X-15799)
- Cefpodoxime Impurity 62 (CAS CATO-C4X-157962)
- Cefpodoxime Proxetil EP Impurity E (CAS 217803-89-9)
- Cefpodoxime Proxetil EP Impurity E (CAS CATO-C4X-157951)
- Cefpodoxime Proxetil EP Impurity F (CAS CATO-C4X-157953)
- Cefpodoxime Proxetil EP Impurity F (CAS 96680-30-7)
Recommended Standards
- Argatroban Impurity 92 (CAS CATO-C4X-100792)
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- Baloxavir Impurity 114 (CAS CATO-C4X-2108114)
- 2-((2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl)thio)-6-(2,5-dimethoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (CAS 939893-60-4)
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