Cefpodoxime Proxetil EP Impurity F CAS CATO-C4X-157953
| CAS No. | CATO-C4X-157953 |
| Molecular Formula | C22H27N5O10S2 |
| Molecular Weight | 585.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 585.61 g/mol gives Cefpodoxime Proxetil EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Cefpodoxime Proxetil EP Impurity F (CAS CATO-C4X-157953) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27N5O10S2 and a molecular weight of 585.61 g/mol.
The molecular framework of Cefpodoxime Proxetil EP Impurity F (C22H27N5O10S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27N5O10S2 |
| Molecular Weight | 585.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefpodoxime Standards
- Cefpodoxime Proxetil EP Impurity E (CAS 217803-89-9)
- Cefpodoxime Proxetil EP Impurity E (CAS CATO-C4X-157951)
- Cefpodoxime Proxetil EP Impurity F (CAS 96680-30-7)
- Cefpodoxime Impurity 60 (CAS CATO-C4X-157960)
- Cefpodoxime Impurity 62 (CAS CATO-C4X-157962)
- Cefpodoxime Proxetil Impurity 10 (CAS CATO-C4X-157910)
- Cefpodoxime Impurity 48 (CAS CATO-C4X-157948)
- Cefpodoxime Impurity 50 (CAS CATO-C4X-157950)
Recommended Standards
- Nafamostat impurity 87 (CAS CATO-C4X-133287)
- 1-(2-(4-Bromo-2-fluorophenoxy)ethyl)-4-(2-((tert-butyldiphenylsilyl)oxy)ethyl)piperazine (CAS 1704081-76-4)
- Nafamostat Impurity 27 (CAS CATO-C4X-133227)
- MK-4232 (Mixture of Diastereomers) (CAS 1263291-17-3)
- Sorafenib EP Impurity A (CAS 284462-37-9)
- Etrasimod Impurity 40 (CAS 2863533-12-2)
- Rotigotine EP Impurity H HCl (CAS 1232344-37-4)
- N-((3-Acetylisoxazol-5-yl)methyl)acetamide (CAS 390817-71-7)
- 4-Bromo-benzooxazole-2-carbaldehyde (CAS 944898-97-9)
- 1-Methyl-4-((2-(pyrrolidin-1-yl)ethoxy)methyl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine (CAS 1422133-17-2)
- 4-((2-Hydroxyethyl)(methyl)amino)picolinic acid (CAS 1178081-92-9)
- Monobenzyl Phthalate (CAS 2528-16-7)
- Erbium carbonate hydrate, 99.90% (CAS 22992-83-2)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
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