Estradiol Valerate EP Impurity B CAS 21881-45-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.21881-45-8
Molecular FormulaC23H32O3
Molecular Weight356.50 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Estradiol Valerate EP Impurity B CAS 21881-45-8 chemical structure

Description

As a certified reference material (CRM), Estradiol Valerate EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies Estradiol Valerate EP Impurity B (CAS 21881-45-8), a pharmacopoeial impurity reference standard (molecular formula C23H32O3, MW 356.50 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C23H32O3, Estradiol Valerate EP Impurity B contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC23H32O3
Molecular Weight356.50 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963

Related Estradiol Standards

Recommended Standards

Why CATO?