Nimodipine EP Impurity B CAS 21881-78-7
| CAS No. | 21881-78-7 |
| Molecular Formula | C21H26N2O6 |
| Molecular Weight | 402.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 402.44 g/mol gives Nimodipine EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nimodipine EP Impurity B (CAS 21881-78-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26N2O6 and a molecular weight of 402.44 g/mol.
Nimodipine EP Impurity B (C21H26N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nimodipine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26N2O6 |
| Molecular Weight | 402.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Nimodipine Standards
- Nimodipine Impurity 10 (CAS CATO-C4X-138510)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510-SS)
- Nimodipine Impurity 12 (CAS CATO-C4X-138512)
- Nimodipine impurity 22 (CAS CATO-C4X-138522)
- Nimodipine Impurity 7 (CAS 82219-48-5)
- Nimodipine Impurity 25 (CAS 82219-47-4)
- Nimodipine Impurity 33 (CAS 39562-75-9)
- Nimodipine Impurity 4 (CAS CATO-C4X-13854)
Recommended Standards
- Cefoxitin Impurity 37 (CAS CATO-C4X-157837)
- Ticarcillin Impurity 10 (CAS CATO-C4X-176310)
- Lercanidipine Impurity 2 (CAS CATO-C4X-13642)
- Ticarcillin EP Impurity D (CAS CATO-C4X-17634)
- Alogliptin Impurity 59 (CAS CATO-C4X-109959)
- CAS CATO-C3D-262723 (CAS CATO-C3D-262723)
- Imatinib Impurity 72 (CAS CATO-C4X-106872)
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- 4-Amino-n-(2-hydroxyethyl)-n-methylpyridine-2-carboxamide (CAS 1248484-11-8)
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- (±)-Nicotine-2，4，5，6-d4 (CAS 350818-69-8)
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