Nimodipine Impurity 33 CAS 39562-75-9
| CAS No. | 39562-75-9 |
| Molecular Formula | C20H24N2O7 |
| Molecular Weight | 404.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Nimodipine Impurity 33 (CAS 39562-75-9, C20H24N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Nimodipine Impurity 33 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 404.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Nimodipine Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O7 |
| Molecular Weight | 404.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 2 |
Related Nimodipine Standards
- Nimodipine Impurity 25 (CAS 82219-47-4)
- Nimodipine Impurity 9 (CAS 116799-92-9)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510-SS)
- Nimodipine Impurity 12 (CAS CATO-C4X-138512)
- Nimodipine EP Impurity B (CAS 21881-78-7)
- Nimodipine impurity 22 (CAS CATO-C4X-138522)
- Nimodipine Impurity 7 (CAS 82219-48-5)
Recommended Standards
- Oseltamivir Impurity 112 (CAS CATO-C4X-1720112)
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
- Nitrendipine Impurity 17 (CAS CATO-C4X-183417)
- Linezolid Impurity 91 (CAS CATO-C4X-107391)
- Mirogabalin Impurity 203 (CAS CATO-C4X-2924203)
- Lubiprostone Impurity 37 (CAS CATO-C4X-113637)
- Prilocaine EP Impurity E HCl (CAS 35891-99-7)
- 1-Boc-3-hydroxyazetidine-3-carbonitrile (CAS 1493737-08-8)
- (4,4-dioxo-1,4-oxathiepan-6-yl)methanamine (CAS 1895475-15-6)
- ethyl 2-{[(2-hydroxyphenyl)methyl]amino}acetate (CAS 57938-78-0)
- 2-amino-n-(3-methoxypropyl)acetamide (CAS 938336-72-2)
- 2-(5-Bromopyridin-3-yl)-4,4-dimethyl-4,5-dihydrooxazole (CAS 923276-49-7)
- (3-Cyclopropyl-5-(1H-imidazol-1-yl)phenyl)boronic acid (CAS 2225173-62-4)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
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