Nimodipine Impurity 7 CAS 82219-48-5
| CAS No. | 82219-48-5 |
| Molecular Formula | C20H22N2O7 |
| Molecular Weight | 402.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nimodipine Impurity 7.
Nimodipine Impurity 7 (CAS 82219-48-5) is a certified pharmaceutical impurity reference standard with the molecular formula C20H22N2O7 and a molecular weight of 402.40 g/mol.
The molecular framework of Nimodipine Impurity 7 (C20H22N2O7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nimodipine Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22N2O7 |
| Molecular Weight | 402.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
Related Nimodipine Standards
- Nimodipine Impurity 10 (CAS CATO-C4X-138510)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510-SS)
- Nimodipine Impurity 12 (CAS CATO-C4X-138512)
- Nimodipine EP Impurity B (CAS 21881-78-7)
- Nimodipine impurity 22 (CAS CATO-C4X-138522)
- Nimodipine Impurity 4 (CAS CATO-C4X-13854)
- Nimodipine Impurity 25 (CAS 82219-47-4)
- Nimodipine Impurity 33 (CAS 39562-75-9)
Recommended Standards
- Olanzapine Impurity 67 (CAS CATO-C4X-117867)
- Finerenone Impurity 160 (CAS CATO-C4X-2880160)
- Olanzapine Embonate Monohydrate EP Impurity F (CAS CATO-C4X-117863)
- Finerenone Impurity 79 (CAS CATO-C4X-288079)
- Ruxolitinib Impurity 81 (CAS CATO-C4X-205881)
- Penicillamine EP Impurity A (CAS 20902-45-8)
- Tolvaptan Impurity 119 (CAS CATO-C4X-1955119)
- N-[(1-propyl-1H-pyrazol-4-yl)methyl]cyclopropanamine (CAS 1170104-52-5)
- 2-(5-Methylpyrimidin-2-yl)butan-2-amine (CAS 1340234-57-2)
- 1-Boc-4-(2-Methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-1-yl)piperidine (CAS 1243415-03-3)
- 2-(4-Nitrophenyl)-1-(piperidin-1-yl)ethan-1-one (CAS 105072-35-3)
- 2-methyl-4-(2-naphthyl)-1,3-thiazole 57493-25-1 (CAS 57493-25-1)
- Desloratadine Dehydro 11-Oxo Impurity (CAS 117811-16-2)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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