Hydroxyzine dihydrochloride CAS 2192-20-3
| CAS No. | 2192-20-3 |
| Molecular Formula | C21H27ClN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Hydroxyzine dihydrochloride is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Hydroxyzine dihydrochloride (CAS 2192-20-3) is a high-purity analytical reference standard with the molecular formula C21H27ClN2O2HCl and a molecular weight of 411.37 g/mol.
Based on its molecular formula C21H27ClN2O2HCl, Hydroxyzine dihydrochloride contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 411.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Hydroxyzine dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27ClN2O2 2*HCl |
| Molecular Weight | 411.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Hydroxyzine Standards
- Hydroxyzine Pamoate (CAS 10246-75-0)
- Hydroxyzine Impurity 9 (CAS 1031-92-1)
- Hydroxyzine-d8DISCONTINUED (CAS 1189480-47-4)
- Hydroxyzine-d4 2HCl (2-hydroxyethoxy-d4) (CAS 1219805-91-0)
- Hydroxyzine Impurity B Hydrochloride salt (CAS 1263283-80-2)
- Hydroxyzine-d8 DiHCl (CAS 1808202-93-8)
- Hydroxyzine Impurity 5 (CAS 2469273-48-9)
- Hydroxyzine Impurity 2 Dimaleate (Etodroxizine Dimaleate) (CAS 56335-21-8)
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- 3-(tert-Butyl)-1-(3-iodo-4-methylphenyl)-1H-pyrazol-5-amine (CAS 294852-50-9)
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Why CATO?
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