Donepezil Impurity 57 CAS 220170-73-0
| CAS No. | 220170-73-0 |
| Molecular Formula | C29H35NO9 |
| Molecular Weight | 541.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Donepezil Impurity 57 (C29H35NO9) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Donepezil Impurity 57 (CAS 220170-73-0) is a certified pharmaceutical impurity reference standard with the molecular formula C29H35NO9 and a molecular weight of 541.59 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Donepezil Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H35NO9 |
| Molecular Weight | 541.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 29 (CAS 197010-25-6)
- Donepezil Impurity 31 (CAS 2097683-67-3)
- Donepezil EP impurity C (CAS 2452407-76-8)
- Donepezil Impurity 7 (CAS 120013-84-5)
- Donepezil Impurity 51 (CAS CATO-C4X-103951)
- Donepezil Impurity 53 (CAS 149874-81-7)
- Donepezil Impurity 74 (CAS CATO-C4X-103974)
- Donepezil Impurity 15 (CAS 1023500-88-0)
Recommended Standards
- N-(1-Benzyl-3-cyano-4,5-dimethyl-1H-pyrrol-2-yl)-4-fluoro-N-(4-fluorobenzenesulfonyl)benzene-1-sulfonamide (CAS 478033-03-3)
- Fluticasone Furoate D3 (CAS 397864-44-7(unlabelled))
- 5-O-Desmethyl Donepezil Glucuronide (Mixture of Diastereomers) (CAS 220170-74-1)
- Di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-(2,2,2-trifluoroacetamido)ethyl)amino)ethyl)azanediyl)diacetate (CAS 180152-84-5)
- Ticagrelor Impurity 184 (R)-Mandelate (CAS 2673270-21-6)
- Oseltamivir EP Impurity E (CAS 208720-71-2)
- Formoterol Impurity 60 (CAS CATO-C4X-152560)
- 1-(2-aminoethyl)cyclopropanamine;dihydrochloride (CAS 1803581-14-7)
- 1,3-Dimethoxybenzene-d10 (CAS 340257-57-0)
- 2-(Difluoromethyl)-3-hydroxy-6-methylpyridine-5-methanol (CAS 1807132-57-5)
- 2,6-Anthracenedisulfonic acid, 4,8-diamino-9,10-dihydro-1,5-dihydroxy-9,10-dioxo- (CAS 128-86-9)
- 3-Amino-4-(trifluoromethyl)pyridine (CAS 175204-80-5)
- 3-{[bis(prop-2-en-1-yl)amino]methyl}-4-methoxybenzaldehyde (CAS 832740-13-3)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com