Apixaban Impurity 40 CAS 2206825-81-0
| CAS No. | 2206825-81-0 |
| Molecular Formula | C25H27N5O5 |
| Molecular Weight | 477.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apixaban Impurity 40 (CAS 2206825-81-0) is a certified pharmaceutical impurity reference standard with the molecular formula C25H27N5O5 and a molecular weight of 477.51 g/mol.
Structurally, Apixaban Impurity 40 (C25H27N5O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 477.51 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apixaban Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H27N5O5 |
| Molecular Weight | 477.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 39 (CAS 2206825-87-6)
- Apixaban Impurity 13 (CAS CATO-C4X-108813)
- Apixaban Impurity 2 (CAS 2187409-01-2)
- Apixaban Impurity 65 (CAS 2264018-89-3)
- Apixaban Impurity 6 (CAS 1074365-84-6)
- Apixaban Impurity 137 (CAS CATO-C4X-1088137)
- Apixaban Impurity 155 (CAS 1928718-22-2)
- Apixaban Impurity 164 (CAS CATO-C4X-1088164)
Recommended Standards
- Aztreonam Impurity 15 (CAS CATO-C4X-152215)
- Methyl 3-(bis(3-(1,3-dioxoisoindolin-2-yl)propyl)amino)propanoate (CAS 364352-26-1)
- Aztreonam impurity 73 (CAS CATO-C4X-152273)
- Dibenzyl (3-(3,4-dihydroxyphenyl)propanoyl)-L-aspartate (CAS 615264-62-5)
- Cabozantinib Impurity 33 (CAS 849217-48-7)
- Neratinib Impurity 31 (CAS CATO-C4X-113431)
- Milrinone Impurity 29 (CAS CATO-C4X-109129)
- Methyl 3-amino-5-chloropicolinate (CAS 866775-11-3)
- 4,4-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1421604-19-4)
- n-(2-Aminoethyl)-3-nitrobenzenesulfonamide (CAS 90607-72-0)
- 3-(iodomethyl)tetrahydropyran (CAS 32730-60-2)
- 1-Methyl-4-(quinolin-3-yl)piperidin-4-ol (CAS 75446-47-8)
- 3-Chloro-2-morpholinopyridine (CAS 54231-36-6)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com