Sorafenib EP Impurity D CAS 2206827-14-5
| CAS No. | 2206827-14-5 |
| Molecular Formula | C17H19N3O4 |
| Molecular Weight | 329.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sorafenib EP Impurity D (CAS 2206827-14-5), a pharmacopoeial impurity reference standard (molecular formula C17H19N3O4, MW 329.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Sorafenib EP Impurity D (C17H19N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sorafenib EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O4 |
| Molecular Weight | 329.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related Sorafenib Standards
- Sorafenib Impurity 41 (CAS 1129683-83-5)
- Sorafenib Impurity 13 (CAS CATO-C4X-112413)
- Sorafenib Impurity 4 (CAS 871555-75-8)
- Sorafenib Impurity 2(PAPE-ethyl carbamate) (CAS 2206827-12-3)
- Sorafenib impurity 64 (CAS CATO-C4X-112464)
- Sorafenib Impurity 29 (CAS CATO-C4X-112429)
- Sorafenib Impurity 35 (CAS CATO-C4X-112435)
- Sorafenib Impurity 11 (CAS 1129683-88-0)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com