Sorafenib Impurity 35 CAS CATO-C4X-112435
| CAS No. | CATO-C4X-112435 |
| Molecular Formula | C17H20F3N3O3 |
| Molecular Weight | 371.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Sorafenib Impurity 35 (CAS CATO-C4X-112435, C17H20F3N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Sorafenib Impurity 35 (C17H20F3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 371.35 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H20F3N3O3 |
| Molecular Weight | 371.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sorafenib Standards
- Sorafenib Impurity 17 (CAS 2004659-83-8)
- Sorafenib Impurity 62 (CAS CATO-C4X-112462)
- Sorafenib Impurity 41 (CAS 1129683-83-5)
- Sorafenib EP Impurity D (CAS 2206827-14-5)
- Sorafenib Impurity 13 (CAS CATO-C4X-112413)
- Sorafenib Impurity 4 (CAS 871555-75-8)
- Sorafenib Impurity 2(PAPE-ethyl carbamate) (CAS 2206827-12-3)
- Sorafenib EP Impurity F (CAS 1285533-84-7)
Recommended Standards
- Acyclovir EP Impurity H (CAS 133186-23-9)
- Methyl 1-(2-ethoxy-2-oxoethyl)-6-(4-fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-28-9)
- 933219-97-7 Ethyl 3-[4-ethyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl]-1,2,4-oxadiazole-5-carboxylate MFCD14716227 (CAS 933219-97-7)
- 3-(Tert-butyl)-1-(5-(trifluoromethyl)pyridin-2-yl)indeno[1,2-c]pyrazol-4(1H)-one (CAS 1024537-54-9)
- Dacomitinib Impurity 7 (CAS CATO-C4X-20867)
- Gadoteridol impurity 38 (CAS CATO-C4X-225738)
- Crisaborole Impurity 28 (CAS CATO-C4X-202128)
- 4H-1,3,5-Oxadiazin-4-one, tetrahydro-3,5-bis(hydroxymethyl)- (CAS 7327-69-7)
- 4-(Bromomethyl)-1,3-dioxol-2-one (CAS 80715-25-9)
- 2-(3,5-Dimethylphenyl)piperazine (CAS 1286754-93-5)
- Methyl 2-ethoxy-5-nitrobenzoate (CAS 80074-34-6)
- ((4-Aminophenyl)sulfonyl)phenylalanine (CAS 1638102-72-3)
- 5-(2-Ethoxyphenyl)oxazolidin-2-one (CAS 1226409-89-7)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com