Idarubicin impurity 13 CAS 220736-88-9
| CAS No. | 220736-88-9 |
| Molecular Formula | C18H10O8 |
| Molecular Weight | 354.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Idarubicin impurity 13 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Idarubicin impurity 13 (CAS 220736-88-9) is a certified pharmaceutical impurity reference standard with the molecular formula C18H10O8 and a molecular weight of 354.27 g/mol.
The molecular framework of Idarubicin impurity 13 (C18H10O8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Idarubicin impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H10O8 |
| Molecular Weight | 354.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
Related Idarubicin Standards
Recommended Standards
- 8-Fluoro-3-(methoxymethoxy)naphthalen-1-yl trifluoromethanesulfonate (CAS 2839526-64-4)
- Suzetrigine Impurity 2 (CAS 2649470-87-9)
- 6-Bromo-8-cyclopentyl-5-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 362656-25-5)
- Suzetrigine Impurity 21 (CAS CATO-C4X-336921)
- Ceritinib Impurity 54 (CAS CATO-C4X-104854)
- Vonoprazan Impurity 138 (CAS CATO-C4X-1020138)
- Revefenacin impurity 98 (CAS CATO-C4X-203198)
- 1,6,7-Trichloroisoquinoline (CAS 1378260-88-8)
- Deschloroketamine hydrochloride (CAS 4631-27-0)
- N-Benzyl-2-((3-cyano-4-(furan-2-yl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)thio)acetamide (CAS 693240-77-6)
- (4<I>S</I>,4′<I>S</I>)-(-)-2,2′-(3-pentenyl)bis(4-isopropyloxazoline) (CAS 160191-65-1)
- Methyl (3S,5S)-5-methylpiperidine-3-carboxylate (CAS 405513-13-5)
- (3S,4R)-1-tert-Butyl 3-methyl 4-(4-chlorophenyl)pyrrolidine-1,3-dicarboxylate (CAS 862284-39-7)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com