Idarubicin Impurity 8 CAS 84499-12-7
| CAS No. | 84499-12-7 |
| Molecular Formula | C20H12O5 |
| Molecular Weight | 332.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Idarubicin Impurity 8.
Idarubicin Impurity 8 (CAS 84499-12-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H12O5 and a molecular weight of 332.31 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, Idarubicin Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Idarubicin Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H12O5 |
| Molecular Weight | 332.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
Related Idarubicin Standards
Recommended Standards
- Lercanidipine Impurity 9 (CAS 74936-72-4)
- Nifedipine Impurity 8 (CAS 74936-71-3)
- 4-methyl-2-[2-(5-methyl-2-nitrophenoxy)ethoxy]-1-nitrobenzene 96315-06-9 (CAS 96315-06-9)
- Zanamivir EP Impurity H (CAS 179531-57-8)
- Goserelin Impurity 16 (CAS CATO-C4X-192016)
- Midazolam EP Impurity E Maleate Salt (CAS CATO-C4X-150922)
- Netupitant Impurity 23 (CAS CATO-C4X-122323)
- 1-((3-(tert-Butyl)-4-ethoxyphenyl)sulfonyl)-2-isopropyl-1H-imidazole (CAS 898640-00-1)
- Ethyl [4-Oxo-4-(phenethylamino)butyl]carbamate (CAS 1477949-42-0)
- 2-methyl-2-(piperazin-1-yl)propanoic acid dihydrochloride (CAS 2059993-02-9)
- 4-Chloro-6-(4-ethylpiperazin-1-yl)-2-methylpyrimidine (CAS 1251204-34-8)
- (2-Cyclohexyl-5-methyloxazol-4-yl)methanol (CAS 89724-31-2)
- Neratinib Impurity 4 (CAS CATO-C4X-11344)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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