Idarubicin impurity 14 CAS 77312-66-4
| CAS No. | 77312-66-4 |
| Molecular Formula | C26H27NO8 |
| Molecular Weight | 481.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Idarubicin impurity 14 (CAS 77312-66-4) is a certified pharmaceutical impurity reference standard with the molecular formula C26H27NO8 and a molecular weight of 481.49 g/mol.
Idarubicin impurity 14 (C26H27NO8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Idarubicin impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H27NO8 |
| Molecular Weight | 481.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Related Idarubicin Standards
- Idarubicin impurity 15 (CAS CATO-C4X-137415)
- Idarubicin (CAS 58957-92-9)
- Idarubicin Isomer (CAS 58957-93-0)
- Idarubicin Impurity 14 (CAS 92999-26-3)
- Idarubicin Impurity 15 (CAS 97777-78-1)
- Idarubicin Impurity 10 (CAS 85440-44-4)
- Idarubicin Impurity 1 (CAS 60660-75-5)
- Idarubicin impurity 13 (CAS 220736-88-9)
Recommended Standards
- 0158AF 5-Bromo-2-chloro-4-(tributylstannyl)pyridine 821773-99-3 C17H29BrClNSn (CAS 821773-99-3)
- Moxifloxacin-¹³Cd3 N-Sulfate Disodium Salt (CAS 234080-64-9)
- Pazopanib Impurity 52 (CAS CATO-C4X-172552)
- Methyl 3-[(4-imino-6,7-dimethoxy-3-{[3-(trifluoromethyl)phenyl]methyl}-3,4-dihydroquinazolin-2-yl)sulfanyl]propanoate (CAS 383146-98-3)
- Iguratimod Impurity 25 HCl (CAS 150831-14-4 (free base))
- Lifitegrast Impurity 53 (CAS 2215846-47-0)
- Carteolol EP Impurity F (CAS 2748462-60-2)
- {3-[(methylsulfanyl)methyl]phenyl}boronic acid (CAS 1333345-25-7)
- (E)-1-(3-Fluorophenyl)but-2-en-1-one (CAS 1809201-85-1)
- 3-Propyltetrahydro-4H-pyran-4-one (CAS 15910-02-8)
- Acipimox Impurity 9 (CAS 25594-37-0)
- 6-(Bromomethyl)-5-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 2883020-29-7)
- 1-(4-Isopropyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride (CAS 1255718-18-3)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com