Alogliptin Impurity 37 CAS 22115-41-9
| CAS No. | 22115-41-9 |
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, Alogliptin Impurity 37 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 196.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Alogliptin Impurity 37 (CAS 22115-41-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6BrN and a molecular weight of 196.04 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Alogliptin Standards
- Alogliptin Impurity 4 (CAS 172603-05-3)
- Alogliptin Related Compound 87 (CAS 1246610-71-8)
- Alogliptin Impurity 66 (CAS 452-63-1)
- Alogliptin Related Compound 83 (CAS 130462-63-4)
- Alogliptin Impurity 68 (CAS 421552-12-7)
- Alogliptin Related Compound 48 (CAS 872414-52-3)
- Alogliptin Related Compound 47 (CAS 7115-89-1)
- Alogliptin Impurity 97 (CAS CATO-C4X-109997)
Recommended Standards
- 4-Cyanobenzyl Bromide (CAS 17201-43-3)
- Letrozole Impurity 39 (CAS 28188-41-2)
- N-(2-Bromoethyl)urethane (CAS 7452-78-0)
- 2,3-Dihydro-5-furanoboronic acid pinacol ester (CAS 1046812-02-5)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Flucloxacillin EP Impurity A (CAS CATO-C4X-164715)
- Acipimox Impurity 9 (CAS 25594-37-0)
- (2E)-1-(4-Bromophenyl)-3-(2-chlorophenyl)prop-2-en-1-one (CAS 86293-48-3)
- 2-(4-Methoxyphenyl)-N-((5-methylthiophen-2-yl)methyl)ethan-1-amine (CAS 874123-63-4)
- (3-Amino-2,6-dichlorophenyl)boronic acid (CAS 2096330-06-0)
- 2-Amino-3-[1-(tert-butoxycarbonyl)-piperidin-4-yl]propanoic acid (CAS 1255666-24-0)
- 2,6-Dichloro-N-ethyl-4-nitroaniline (CAS 101257-57-2)
- 2-Methyl-1-oxo-1,2-dihydroisoquinoline-4-carbohydrazide (CAS 1171808-03-9)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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