Osimertinib Impurity 12 CAS 2213409-62-0
| CAS No. | 2213409-62-0 |
| Molecular Formula | C23H20FN5O2 |
| Molecular Weight | 417.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Osimertinib Impurity 12 (CAS 2213409-62-0), a pharmacopoeial impurity reference standard (molecular formula C23H20FN5O2, MW 417.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H20FN5O2, Osimertinib Impurity 12 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 417.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Osimertinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H20FN5O2 |
| Molecular Weight | 417.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Osimertinib Standards
- Osimertinib Impurity N3 (CAS 1820891-36-8)
- Osimertinib Impurity 45 (CAS CATO-C4X-204545)
- Osimertinib Impurity 62 (CAS CATO-C4X-204562)
- Osimertinib Impurity 3 (AZD9291 Impurity 3) (CAS CATO-C4X-20453)
- Osimertinib Impurity 66 (CAS CATO-C4X-204566)
- Osimertinib Impurity 94 (CAS 1942853-18-0)
- Osimertinib Impurity 16 (CAS 2044704-62-1)
- Osimertinib Impurity 54 (CAS 27065-95-8)
Recommended Standards
- N-(5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-3-(ethylsulfonyl)benzamide (CAS 886919-92-2)
- Oxacillin Impurity 43 (CAS CATO-C4X-232143)
- N-(4-(3-Nitrophenyl)thiazol-2-yl)-4-phenoxybenzamide (CAS 313404-06-7)
- Oxacillin Impurity 9 (CAS CATO-C4X-23219)
- Sitafloxacin impurity 70 (CAS CATO-C4X-115570)
- Relugolix Impurity 95 (CAS CATO-C4X-242995)
- Fesoterodine Impurity 1 (CAS 250214-44-9)
- Ibrutinib Impurity 156 (CAS 1642601-01-1)
- (Tetrahydro-2H-thiopyran-3-yl)methanamine (CAS 1369145-95-8)
- Ethyl 3-amino-3-(3-bromo-4-ethylphenyl)propanoate hydrochloride (CAS 502842-17-3)
- 1-(5,6-Dimethoxypyridin-2-yl)ethanone (CAS 1203499-03-9)
- 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole (CAS 338777-18-7)
- (5-Isobutylpyridin-3-yl)boronic acid (CAS 1952356-61-4)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com