Lifitegrast Impurity 53 CAS 2215846-47-0
| CAS No. | 2215846-47-0 |
| Molecular Formula | C14H17Cl2NO2 |
| Molecular Weight | 302.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lifitegrast Impurity 53 (CAS 2215846-47-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H17Cl2NO2 and a molecular weight of 302.20 g/mol.
Based on its molecular formula C14H17Cl2NO2, Lifitegrast Impurity 53 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 302.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lifitegrast Impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17Cl2NO2 |
| Molecular Weight | 302.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 129 (CAS 2605229-68-1)
- Lifitegrast Impurity 130 (CAS CATO-C4X-2409130)
- Lifitegrast Impurity 162 (CAS CATO-C4X-2409162)
- Lifitegrast Impurity 142 (CAS 2098810-32-1)
- Lifitegrast Impurity 84 (CAS CATO-C4X-240984)
- Lifitegrast Impurity 40 (CAS CATO-C4X-240940)
- Lifitegrast Impurity 106 (CAS CATO-C4X-2409106)
- Lifitegrast Impurity 113 (CAS CATO-C4X-2409113)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com