Lifitegrast Impurity 142 CAS 2098810-32-1
| CAS No. | 2098810-32-1 |
| Molecular Formula | C16H16ClNO2 |
| Molecular Weight | 289.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lifitegrast Impurity 142 (CAS 2098810-32-1), a pharmacopoeial impurity reference standard (molecular formula C16H16ClNO2, MW 289.76 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lifitegrast Impurity 142 (C16H16ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 289.76 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Lifitegrast Impurity 142 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO2 |
| Molecular Weight | 289.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 162 (CAS CATO-C4X-2409162)
- Lifitegrast Impurity 113 (CAS CATO-C4X-2409113)
- Lifitegrast Impurity 53 (CAS 2215846-47-0)
- Lifitegrast Impurity 120 (CAS CATO-C4X-2409120)
- Lifitegrast Impurity 61 (CAS CATO-C4X-240961)
- Lifitegrast Impurity 129 (CAS 2605229-68-1)
- Lifitegrast Impurity 130 (CAS CATO-C4X-2409130)
- Lifitegrast Impurity N4 (CAS 58123-77-6)
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- Blonanserin Impurity 15 (CAS 132813-14-0)
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- Torasemide Impurity 12 (CAS 99300-68-2)
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- 2-Allylphenol (CAS 1745-81-9)
- Vibegron Impurity 7 (CAS CATO-C4X-23767)
- Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethyl-3,5-dimethoxybenzylamine)palladium(II)] (CAS 1093348-08-3)
- Ethyl 4,5-dimethyl-4H-1,2,4-triazole-3-carboxylate (CAS 1341358-71-1)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com