Lifitegrast Impurity 130 CAS CATO-C4X-2409130
| CAS No. | CATO-C4X-2409130 |
| Molecular Formula | C15H18ClNO4 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lifitegrast Impurity 130 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Lifitegrast Impurity 130 (CAS CATO-C4X-2409130), a pharmacopoeial impurity reference standard (molecular formula C15H18ClNO4, MW 311.76 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lifitegrast Impurity 130 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H18ClNO4 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 129 (CAS 2605229-68-1)
- Lifitegrast Impurity 84 (CAS CATO-C4X-240984)
- Lifitegrast Impurity 40 (CAS CATO-C4X-240940)
- Lifitegrast Impurity 53 (CAS 2215846-47-0)
- Lifitegrast Impurity 106 (CAS CATO-C4X-2409106)
- Lifitegrast Impurity 77 (CAS CATO-C4X-240977)
- Lifitegrast Impurity 133 (CAS CATO-C4X-2409133)
- Lifitegrast Impurity 162 (CAS CATO-C4X-2409162)
Recommended Standards
- N-(5-Chloro-2-methylphenyl)-3-hydroxy-2-naphthylcarboxamide (CAS 135-63-7)
- Methotrexate Impurity 76 (CAS CATO-C4X-115476)
- Triadimenol-tert-butylhydroxy (CAS 72699-18-4)
- 2391AF 6-Chloro-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid 897559-93-2 C18H14ClNO2 (CAS 897559-93-2)
- Empagliflozin impurity 237 (CAS CATO-C4X-1065237)
- Ramosetron Impurity 28 (CAS CATO-C4X-118228)
- Darunavir Impurity 18 (CAS 1932330-83-0)
- 2,6-Dimethyl-3-morpholinomethyl benzophenone (CAS 898765-62-3)
- 2-bromo-N-(2-furylmethyl)butanamide (CAS 1105192-34-4)
- Methyl 3-[(aminocarbonyl)amino]-3-phenylpropanoate (CAS 306277-62-3)
- (2R,3R,4R,5R,6R)-3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate (CAS 10385-50-9)
- 3,5-Difluorobenzhydrol (CAS 153877-56-6)
- 2-Amino-5-hydroxyhexanoic acid (CAS 5873-15-4)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com