Lifitegrast Impurity 129 CAS 2605229-68-1
| CAS No. | 2605229-68-1 |
| Molecular Formula | C15H18ClNO4 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 311.76 g/mol gives Lifitegrast Impurity 129 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Lifitegrast Impurity 129 (CAS 2605229-68-1), a pharmacopoeial impurity reference standard (molecular formula C15H18ClNO4, MW 311.76 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lifitegrast Impurity 129 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lifitegrast Impurity 129 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H18ClNO4 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 130 (CAS CATO-C4X-2409130)
- Lifitegrast Impurity 84 (CAS CATO-C4X-240984)
- Lifitegrast Impurity 40 (CAS CATO-C4X-240940)
- Lifitegrast Impurity 53 (CAS 2215846-47-0)
- Lifitegrast Impurity 106 (CAS CATO-C4X-2409106)
- Lifitegrast Impurity 77 (CAS CATO-C4X-240977)
- Lifitegrast Impurity 133 (CAS CATO-C4X-2409133)
- Lifitegrast Impurity 162 (CAS CATO-C4X-2409162)
Recommended Standards
- Methotrexate Impurity 76 (CAS CATO-C4X-115476)
- 2391AF 6-Chloro-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid 897559-93-2 C18H14ClNO2 (CAS 897559-93-2)
- N-(5-Chloro-2-methylphenyl)-3-hydroxy-2-naphthylcarboxamide (CAS 135-63-7)
- N-Benzyl-5-(2-chlorophenyl)furan-2-carboxamide (CAS 618402-74-7)
- Epalrestat Impurity 4 (CAS 1151944-57-8)
- Indapamide Impurity 34 (CAS CATO-C4X-140034)
- Ezetimibe Impurity 41 (CAS CATO-C4X-109841)
- (S)-2-(4-(trifluoromethyl)phenyl)pyrrolidine (CAS 1217816-57-3)
- 6-Bromo-1-ethyl-3,4-dihydroquinolin-2(1H)-one (CAS 1092523-04-0)
- Levonorgestrel EP Impurity T (CAS 14507-51-8)
- 1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-indazol-4-amine (CAS 697739-02-9)
- N-Nitrosodiisobutylamine (CAS 997-95-5)
- 2-Methoxy-4-(methylthio)pyridine-5-boronic acid pinacol ester (CAS 1451392-19-0)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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