Progesterone Impurity 17 CAS 2243-08-5
| CAS No. | 2243-08-5 |
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Progesterone Impurity 17 (CAS 2243-08-5, C21H28O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Progesterone Impurity 17 (C21H28O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Progesterone Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Progesterone Standards
- Progesterone Impurity 1 (CAS 37717-13-8)
- Progesterone Impurity 41 (CAS 2477-60-3)
- Progesterone Impurity 42 (CAS 1173998-80-5)
- Progesterone Impurity 78 (CAS CATO-C4X-150278)
- (20R)-Progesterone EP Impurity I (CAS 66289-21-2)
- Progesterone Impurity N5 (CAS 35525-27-0)
- Progesterone Impurity N1(Mixture of Diastereomers) (CAS 71658-22-5)
- Progesterone EP Impurity I (S-isomer) (CAS 3986-89-8)
Recommended Standards
- Rivastigmine impurity 34 (CAS CATO-C4X-138434)
- Abiraterone Impurity 49 (CAS CATO-C4X-107049)
- Abiraterone Impurity 47 (CAS CATO-C4X-107047)
- Mirabegron Impurity 148 (CAS 1684452-92-3)
- Amlodipine Impurity 80 (CAS CATO-C4X-109580)
- Pazufloxacin lmpurity21 HCI (CAS 171567-51-4)
- Peramivir impurity 151 (CAS 168958-19-8)
- 2-Fluoro-6-(3-fluorophenoxy)aniline (CAS 1184275-63-5)
- 3-((Benzylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide (CAS 950763-16-3)
- (4-(Allyloxy)-3-methoxyphenyl)methanamine (CAS 952946-76-8)
- 4-Bromo-2-methoxy-6-[(1E)-({[3-(trifluoromethyl)phenyl]methyl}imino)methyl]phenol (CAS 478047-10-8)
- Diethyl cyclobutane-1,3-dicarboxylate (CAS 91057-77-1)
- 6-Chlorochroman-3-one (CAS 26371-48-2)
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