Progesterone EP Impurity I (S-isomer) CAS 3986-89-8
| CAS No. | 3986-89-8 |
| Molecular Formula | C22H32O2 |
| Molecular Weight | 328.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Progesterone EP Impurity I (S-isomer) (CAS 3986-89-8), a pharmacopoeial impurity reference standard (molecular formula C22H32O2, MW 328.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Progesterone EP Impurity I (S-isomer) (C22H32O2) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 328.49 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Progesterone EP Impurity I (S-isomer) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H32O2 |
| Molecular Weight | 328.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Progesterone Standards
- (20R)-Progesterone EP Impurity I (CAS 66289-21-2)
- Progesterone Impurity N5 (CAS 35525-27-0)
- Progesterone Impurity N1(Mixture of Diastereomers) (CAS 71658-22-5)
- Progesterone EP Impurity I (CAS 24254-01-1)
- Progesterone Impurity 43 (CAS CATO-C4X-150243)
- Progesterone Impurity 45 (CAS CATO-C4X-150245)
- Progesterone Impurity 51 (CAS 103858-15-7)
- Progesterone Impurity 53 (CAS 903-03-7)
Recommended Standards
- Spironolactone Impurity 10 (CAS 53866-23-2)
- (9-cis,13-cis)-Retinoic Acid Ethyl Ester 86708-68-1 (CAS 86708-68-1)
- CAS 749266-38-4 (CAS 749266-38-4)
- CAS 749266-29-3 (CAS 749266-29-3)
- Valganciclovir Impurity 32 (CAS 960582-59-6)
- Amoxicillin Impurity 89 (CAS CATO-C4X-114889)
- Remimazolam Impurity 15 (CAS CATO-C4X-282315)
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Why CATO?
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