Progesterone Impurity 41 CAS 2477-60-3
| CAS No. | 2477-60-3 |
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Progesterone Impurity 41.
As a process- or degradation-related impurity, Progesterone Impurity 41 (CAS 2477-60-3, C21H28O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, a hydroxyl group, an ether linkage, Progesterone Impurity 41 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Progesterone Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Progesterone Standards
- Progesterone Impurity 1 (CAS 37717-13-8)
- Progesterone Impurity 17 (CAS 2243-08-5)
- Progesterone Impurity 42 (CAS 1173998-80-5)
- Progesterone Impurity 78 (CAS CATO-C4X-150278)
- (20R)-Progesterone EP Impurity I (CAS 66289-21-2)
- Progesterone Impurity N5 (CAS 35525-27-0)
- Progesterone Impurity N1(Mixture of Diastereomers) (CAS 71658-22-5)
- Progesterone EP Impurity I (S-isomer) (CAS 3986-89-8)
Recommended Standards
- Rivastigmine impurity 34 (CAS CATO-C4X-138434)
- Abiraterone Impurity 49 (CAS CATO-C4X-107049)
- Cyproterone Impurity 4 (CAS 2477-61-4)
- Abiraterone Impurity 47 (CAS CATO-C4X-107047)
- Prasugrel Impurity N1 (CAS 201049-78-7)
- Benidipine Impurity 51 (CAS CATO-C4X-112051)
- Bilastine Impurity 12 Formate (CAS 2099128-83-1(free base))
- Methyl 4-(aminomethyl)-2-methoxybenzoate hydrochloride (CAS 1391358-23-8)
- 2-(2,6-Dichlorophenyl)-3-oxobutanenitrile (CAS 186196-04-3)
- Iodosulfuron (CAS 185119-76-0)
- 5-Bromo-2-chloro-N4-methylpyridine-3,4-diamine (CAS 1590410-28-8)
- 4-Bromo-3-(2-fluorophenyl)-1-methyl-1H-pyrazole (CAS 924287-92-3)
- Methyl (1S,9S)-9-amino-6,10-dioxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylate (CAS 348109-83-1)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com