Aripiprazole Impurity 18 CAS 2250242-47-6
| CAS No. | 2250242-47-6 |
| Molecular Formula | C27H33Cl2N3O3 |
| Molecular Weight | 518.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Aripiprazole Impurity 18 (C27H33Cl2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 518.48 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Aripiprazole Impurity 18 (CAS 2250242-47-6, C27H33Cl2N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Aripiprazole Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H33Cl2N3O3 |
| Molecular Weight | 518.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Aripiprazole Standards
- Aripiprazole Impurity 89 (CAS CATO-C4X-100889)
- Aripiprazole Impurity N2 (CAS 2220149-92-6)
- Aripiprazole Impurity 31 (CAS 2748381-51-1)
- Aripiprazole Impurity 88 (CAS CATO-C4X-100888)
- Aripiprazole-d8 N,N-Dioxide (CAS 1346603-98-2)
- Aripiprazole Impurity 45 (CAS CATO-C4X-100845)
- Aripiprazole N,N-Dioxide (CAS 573691-13-1)
- Aripiprazole-d8 N1-Oxide (CAS 1346600-34-7)
Recommended Standards
- BAL30072 (CAS 941285-15-0)
- (3-Amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(3,4-dimethoxyphenyl)methanone (CAS 489400-81-9)
- 1-(((Z)-(1-(2-Aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropanecarboxylic acid (CAS 1810051-96-7)
- Phellamurin (CAS 52589-11-4)
- Cyclophosphamide EP Impurity A (CAS 1797009-12-1)
- Amlodipine impurity 127 (CAS CATO-C4X-1095127)
- Niraparib Impurity 36 (CAS 1140736-91-9)
- 1-(Cyclobutylmethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1465204-73-2)
- N-(4-Hydroxy-phenyl)-N-methyl-benzenesulfonamide (CAS 34523-31-4)
- N,1-dimethyl-4-nitro-1H-pyrazole-5-carboxamide (CAS 1260379-36-9)
- 4-Bromo-2-chloro-5-(trifluoromethyl)benzaldehyde (CAS 1414870-64-6)
- 4-(cHloromethyl)-n-phenylbenzamide (CAS 226250-00-6)
- Mirogabalin Impurity 82 (CAS 1246542-63-1)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com