Olaparib Impurity 11 CAS 2250242-62-5
| CAS No. | 2250242-62-5 |
| Molecular Formula | C36H28F2N6O4 |
| Molecular Weight | 646.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Olaparib Impurity 11 (CAS 2250242-62-5) is a certified pharmaceutical impurity reference standard with the molecular formula C36H28F2N6O4 and a molecular weight of 646.64 g/mol.
Structurally, Olaparib Impurity 11 (C36H28F2N6O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 25.0, corresponding to approximately 25 ring(s) or double-bond equivalent(s). With a molecular weight of 646.64 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Olaparib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C36H28F2N6O4 |
| Molecular Weight | 646.64 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Olaparib Standards
- Olaparib Impurity 29 (CAS CATO-C4X-113529)
- Olaparib Impurity 138 (CAS CATO-C4X-1135138)
- Olaparib Impurity 4 (CAS CATO-C4X-11354)
- Olaparib Impurity 162 (CAS CATO-C4X-1135162)
- Olaparib Impurity 40 (CAS CATO-C4X-113540)
- Olaparib Impurity 49 (CAS CATO-C4X-113549)
- Olaparib Impurity N12 (CAS 763114-04-1)
- Olaparib Impurity 28 (CAS 1187479-72-6)
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