Propafenone EP Impurity D CAS 91401-73-9
| CAS No. | 91401-73-9 |
| Molecular Formula | C18H20O4 |
| Molecular Weight | 300.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Propafenone EP Impurity D (CAS 91401-73-9), a pharmacopoeial impurity reference standard (molecular formula C18H20O4, MW 300.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H20O4, Propafenone EP Impurity D contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20O4 |
| Molecular Weight | 300.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
Related Propafenone Standards
- Propafenone EP Impurity C (CAS 22525-95-7)
- Propafenone Hydrochloride EP Impurity C (CAS CATO-C4X-132238)
- Propafenone EP Impurity E (CAS 165279-79-8)
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
- Propafenone Impurity 39 (CAS CATO-C4X-132239)
- Propafenone Impurity 40 (CAS CATO-C4X-132240)
- Propafenone RC 6 (CAS 189766-45-8)
- (R)-Propafenone (CAS 107381-31-7)
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Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com