Propafenone RC 6 CAS 189766-45-8
| CAS No. | 189766-45-8 |
| Molecular Formula | C17H18O3 |
| Molecular Weight | 270.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Propafenone RC 6.
Propafenone RC 6 (CAS 189766-45-8), molecular formula C17H18O3 and molecular weight 270.32 g/mol, is a CATO reference standard with documented purity and traceability.
Propafenone RC 6 (C17H18O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18O3 |
| Molecular Weight | 270.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
Related Propafenone Standards
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
- Propafenone EP Impurity C (CAS 22525-95-7)
- Propafenone Hydrochloride EP Impurity C (CAS CATO-C4X-132238)
- Propafenone EP Impurity D (CAS 91401-73-9)
- Propafenone Impurity 31 (CAS CATO-C4X-132231)
- Propafenone EP Impurity A (CAS 3516-95-8)
- Propafenone Impurity 28 (CAS CATO-C4X-132228)
- Propafenone Impurity 29 (CAS 36941-00-1)
Recommended Standards
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- (3-(2-[2-(2-Methoxyethoxy)ethoxy]ethoxy)phenyl)methanol (CAS 1920136-92-0)
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- 5411-13-2 AR-1I9453 ethyl 5-methyl-2-{[(4-methylphenyl)sulfonyl]amino}-4-phenyl-3-thiophenecarboxylate (CAS 5411-13-2)
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