2-(3-(Difluoromethyl)-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2304635-41-2
| CAS No. | 2304635-41-2 |
| Molecular Formula | C14H19BF2O3 |
| Molecular Weight | 284.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 284.11 g/mol gives 2-(3-(Difluoromethyl)-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-(Difluoromethyl)-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2304635-41-2), molecular formula C14H19BF2O3 and molecular weight 284.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-(3-(Difluoromethyl)-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BF2O3 |
| Molecular Weight | 284.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 2-(4-(Difluoromethyl)-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1310949-77-9)
- 5-(Difluoromethyl)-3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 2923542-41-8)
- 6-(Difluoromethyl)-4-iodo-3-methylpyridin-2-amine (CAS 1805013-27-7)
- 5-(Difluoromethyl)-3-iodo-2-methylpyridin-4-amine (CAS 1805132-41-5)
- 3-(Difluoromethyl)-5-iodo-6-methylpyridin-2-amine (CAS 1805210-50-7)
- 2-(Difluoromethyl)-3-iodo-5-methylpyridin-4-amine (CAS 1805211-13-5)
- (2-(Difluoromethyl)-6-iodopyridin-4-yl)methanamine (CAS 1805308-54-6)
- 6-(Difluoromethyl)-2-iodo-3-methylpyridin-4-amine (CAS 1805331-47-8)
Recommended Standards
- 2-(2-Ethoxy-3,4-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2877757-14-5)
- 2-(3-Bromopropoxy)-2,3-dihydro-1h-isoindole-1,3-dione (CAS 5181-36-2)
- 2-(2-Bromo-6-ethoxy-4-formylphenoxy)acetonitrile (CAS 832674-63-2)
- 2-(3-Ethoxy-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121512-90-9)
- 5-(Pyridin-3-yl)-4h-1,2,4-triazol-3-amine (CAS 35607-27-3)
- 4-(4-Chlorophenyl)-N-cyclopropyl-5-methylthiazol-2-amine (CAS 949640-99-7)
- 8-Hydroxy-N-(3-(imidazo[1,2-a]pyridin-2-yl)phenyl)-2-oxo-2H-chromene-3-carboxamide (CAS 1170689-68-5)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-05-1)
- 2-(Difluoromethyl)-4-fluoro-6-hydroxypyridine-3-acetonitrile (CAS 1806848-98-5)
- 2-Acetamidothiophene-3-carboxylic acid (CAS 51419-38-6)
- 2-(Thiophen-3-ylmethyl)cyclohexan-1-ol (CAS 1304383-81-0)
- N-(3-(1H-Benzo[d]imidazol-2-yl)-4-hydroxyphenyl)acetamide (CAS 1706450-86-3)
- Gefitinib Impurity 34 (CAS CATO-C4X-111734)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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