2-Chloro-4-(trifluoromethyl)benzoic acid CAS 23228-45-7
| CAS No. | 23228-45-7 |
| Molecular Formula | C8H4ClF3O2 |
| Molecular Weight | 224.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-4-(trifluoromethyl)benzoic acid (CAS 23228-45-7), a certified reference material (molecular formula C8H4ClF3O2, MW 224.56 g/mol) for analytical method development and quality control.
2-Chloro-4-(trifluoromethyl)benzoic acid (C8H4ClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-4-(trifluoromethyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF3O2 |
| Molecular Weight | 224.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(3-Chloro-4-fluorophenyl)-2,2-difluoroacetic acid (CAS 1027514-19-7)
- 2-Chloro-4-(trifluoromethoxy)benzaldehyde (CAS 1079351-20-4)
- 5-Chloro-2-(trifluoromethoxy)benzaldehyde (CAS 1092461-15-8)
- 3-Chloro-4-(trifluoromethyl)benzoic Acid (CAS 115754-20-6)
- Methyl 3-chloro-2,4,5-trifluorobenzoate (CAS 1214375-02-6)
- 4-Chloro-2-(trifluoromethoxy)benzaldehyde (CAS 1261442-48-1)
- 3-Chloro-2-(trifluoromethoxy)benzaldehyde (CAS 1261498-32-1)
- 2-Chloro-6-(trifluoromethoxy)benzaldehyde (CAS 1261822-56-3)
Recommended Standards
- 2-Chloro-3-(trifluoromethyl)benzoic Acid (CAS 39226-97-6)
- 2-Chloro-5-(trifluoromethoxy)benzaldehyde (CAS 468075-02-7)
- 2-Chloro-3-(trifluoromethoxy)benzaldehyde (CAS 937069-71-1)
- 2-Chloro-5-(trifluoromethyl)benzoic Acid (CAS 657-06-7)
- (4'-Hydroxy-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261947-62-9)
- (S)-1-(Benzo[d]thiazol-2-yl)ethan-1-amine (CAS 1169393-54-7)
- 3-(2-(Thiophen-3-yl)acetamido)tetrahydrothiophene-3-carboxylic acid (CAS 1285549-89-4)
- 1-Methyl-4-propyl-3-(thiophen-2-yl)-1h-pyrazol-5-amine (CAS 1174308-97-4)
- 3,5-Dichloro-4-(3-pyrrolinomethyl) benzophenone (CAS 898764-71-1)
- 1-(5-Iodopyrimidin-4-yl)azepane (CAS 1497040-50-2)
- 3,4-Diethoxybenzohydrazide (CAS 380482-31-5)
- 1-Phenyl-3-(3-propoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 1234692-21-7)
- 5-Thio-D-glucose-6-phosphate diammonium salt (CAS 108391-99-7)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com