Verapamil Impurity N1 CAS 102201-30-9
| CAS No. | 102201-30-9 |
| Molecular Formula | C16H20N2O2 |
| Molecular Weight | 272.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Verapamil Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Verapamil Impurity N1 (CAS 102201-30-9) is a certified pharmaceutical impurity reference standard with the molecular formula C16H20N2O2 and a molecular weight of 272.34 g/mol.
The molecular framework of Verapamil Impurity N1 (C16H20N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H20N2O2 |
| Molecular Weight | 272.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil EP Impurity D (CAS 36770-74-8)
- Verapamil Impurity 17 (CAS CATO-C4X-177817)
- Verapamil Impurity 20 (CAS 27339-25-9)
- Verapamil Impurity 33 (CAS 27487-66-7)
- Verapamil Impurity 19 (CAS CATO-C4X-177819)
- Verapamil EP Impurity F (CAS 34245-14-2)
- Verapamil Impurity 51 (CAS CATO-C4X-177851)
- Verapamil Impurity 52 (CAS CATO-C4X-177852)
Recommended Standards
- 2-{[(tert-Butoxy)carbonyl]amino}-3-(piperidin-4-yl)propanoic acid (CAS 1021943-61-2)
- N-{2-[(5,5-dimethyl-3-oxocyclohex-1-en-1-yl)amino]phenyl}acetamide (CAS 1024287-62-4)
- [3-methoxy-4-(3-phenylpropoxy)phenyl]methanol (CAS 1021030-78-3)
- 1-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-3-phenyl-1H-pyrazol-5(4H)-one (CAS 102689-15-6)
- Serotonin Impurity N2 (CAS 1134-01-6)
- Foritinib Impurity 13 (CAS CATO-C4X-331013)
- Pramipexole Impurity 10 (CAS CATO-C4X-110710)
- (2-Methoxy-6-(methoxycarbonyl)pyridin-4-yl)boronic acid (CAS 2225179-69-9)
- 4-(Tert-butyl)piperidin-4-ol (CAS 73617-82-0)
- [(1S)-3,3-Difluorocyclopentyl]methanamine (CAS 1408057-46-4)
- 2-Ethynyl-2'-methoxy-1,1'-biphenyl (CAS 445262-74-8)
- Methyl 4-(4-methoxyphenoxy)benzoate (CAS 38342-84-6)
- 5-Methyl-4-phenyl-thiophene-3-carboxylic acid 557792-56-0 5609AE C12H10O2S (CAS 557792-56-0)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com