Ezetimibe Impurity 107 CAS 2363086-22-8
| CAS No. | 2363086-22-8 |
| Molecular Formula | C33H30F2N2O5 |
| Molecular Weight | 572.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ezetimibe Impurity 107 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ezetimibe Impurity 107 (CAS 2363086-22-8) is a certified pharmaceutical impurity reference standard with the molecular formula C33H30F2N2O5 and a molecular weight of 572.60 g/mol.
Structurally, Ezetimibe Impurity 107 (C33H30F2N2O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 572.60 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C33H30F2N2O5 |
| Molecular Weight | 572.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ezetimibe Standards
- Ezetimibe Impurtiy N5 (CAS 1621715-63-6)
- Ezetimibe Impurity 105 (CAS 1296129-16-2)
- Ezetimibe Impurity N13 (CAS 1185883-40-2)
- Ezetimibe Impurity 78 (CAS CATO-C4X-109878)
- Ezetimibe Impurity 120 (CAS 1197343-09-1)
- Ezetimibe Impurity 40 (CAS 190448-57-8)
- Ezetimibe Hydroxy Glucuronide (CAS 536709-33-8)
- Ezetimibe Phenoxy Glucuronide-d4 (CAS 1426174-41-5)
Recommended Standards
- Ceftriaxone Impurity 20 (CAS CATO-C4X-116320)
- BMS-986142 (CAS 1643368-58-4)
- Ceftriaxone Impurity 21 (CAS CATO-C4X-116321)
- Ceftriaxone Impurity 32 (CAS CATO-C4X-116332)
- Drotaverin Impurity 45 (CAS 855199-57-4)
- Oxytetracycline EP Impurity C (CAS 7647-65-6)
- Avibactam Impurity 70 (CAS CATO-C4X-134870)
- N-(2-Bromo-6-nitrophenyl)-N-isopropylacetamide (CAS 1147015-08-4)
- Nitenpyram-13C3-15N2 (CAS CATO-CCPD102478)
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- 5-Chloro-3-methoxybenzene-1,2-diamine (CAS 1255789-24-2)
- 7-bromo-1,2-dihydroquinazolin-2-one (CAS 953039-65-1)
- 3-(4-Methoxy-2-methylphenyl)-5-phenyl-1H-1,2,4-triazole (CAS 85303-97-5)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
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