4-Chloro-3-fluoro-2-methylphenylboronic acid CAS 2377606-88-5
| CAS No. | 2377606-88-5 |
| Molecular Formula | C7H7BClFO2 |
| Molecular Weight | 188.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-fluoro-2-methylphenylboronic acid.
4-Chloro-3-fluoro-2-methylphenylboronic acid (CAS 2377606-88-5), molecular formula C7H7BClFO2 and molecular weight 188.39 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-3-fluoro-2-methylphenylboronic acid (C7H7BClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-fluoro-2-methylphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7BClFO2 |
| Molecular Weight | 188.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (5-Chloro-2-fluoro-4-methylphenyl)boronic acid (CAS 1072952-42-1)
- 2-Chloro-4-fluoro-5-methylphenylboronic acid (CAS 1207428-93-0)
- (2-Chloro-6-fluorobenzyl)boronic acid (CAS 1350512-24-1)
- 2-Chloro-5-fluoro-4-methylphenylboronic acid (CAS 1612184-35-6)
- (3-Chloro-2-fluoro-4-methylphenyl)boronic acid (CAS 2377608-77-8)
- (3-Chloro-2-fluoro-5-methylphenyl)boronic acid (CAS 352535-88-7)
- (4-Chloro-2-fluoro-3-methylphenyl)boronic acid (CAS 944128-92-1)
- (4-Chloro-2-fluoro-5-methylphenyl)boronic acid (CAS 325786-09-2)
Recommended Standards
- 2-Chloro-6-fluoro-3-methylphenylboronic Acid (CAS 352535-85-4)
- 4-Chloro-5-fluoro-2-methylphenylboronic acid (CAS 2055778-22-6)
- 2-Chloro-5-fluoro-3-methylphenylboronic acid (CAS 2121511-44-0)
- 6-Chloro-2-fluoro-3-methylphenylboronic Acid (CAS 352535-86-5)
- 2-(4-Bromo-3-(N-(tert-butyl)sulfamoyl)phenyl)acetic acid (CAS 2489440-86-8)
- Ethyl 4-(2,6-dichlorophenyl)-3-oxobutanoate (CAS 221121-45-5)
- 2,2,2-Trifluoroethyl n-(2-fluorophenyl)carbamate (CAS 200876-83-1)
- 2,5-Dimethylpyrazolo[1,5-a]pyrimidine (CAS 1263060-58-7)
- Ilaprazole Impurity 161 (CAS CATO-C4X-1130161)
- Methyl 6-fluoro-1,2,3,4-tetrahydroisoquinoline-1-carboxylate hydrochloride (CAS 2007908-42-9)
- 3-Hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1-(3-morpholinopropyl)-5-(pyridin-3-yl)-1H-pyrrol-2(5H)-one (CAS 510712-22-8)
- 6-Nitro-2-phenylquinoline-4-carboxylic Acid (CAS 871883-56-6)
- 3-(4-Cyclohexylphenyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1177298-23-5)
- Peptide 434 (CAS CATO-CPTD788434)
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