5-Chloro-2,3-difluorophenylboronic acid CAS 2377610-07-4
| CAS No. | 2377610-07-4 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2,3-difluorophenylboronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-2,3-difluorophenylboronic acid (CAS 2377610-07-4) is a high-purity analytical reference standard with the molecular formula C6H4BClF2O2 and a molecular weight of 192.36 g/mol.
Based on its molecular formula C6H4BClF2O2, 5-Chloro-2,3-difluorophenylboronic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 192.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-2,3-difluorophenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5)
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- (3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
Recommended Standards
- 4-Chloro-3,5-difluorophenylboronic Acid (CAS 864759-63-7)
- 5-Chloro-2,4-difluorophenylboronic Acid (CAS 911645-24-4)
- 4-Chloro-2,5-difluorophenylboronic acid (CAS 2055778-26-0)
- Propofol Impurity 23 (CAS CATO-C4X-147323)
- Quinolin-7-yl trifluoromethanesulfonate (CAS 163485-84-5)
- 3-Chloro-4-[(pyrrolidin-1-yl)carbonyl]aniline (CAS 209959-69-3)
- Poly(perfluoropropylene Oxide) (CAS 25038-02-2)
- N-(3-fluorobenzyl)-4-methoxyaniline (CAS 415968-77-3)
- ethyl 7-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1403766-98-2)
- 3-Amino-N-(2-methoxy-5-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625370-66-3)
- 4-(2-aminoethyl)azepan-4-ol (CAS 1565393-02-3)
- 6-Methoxy-7-nitroquinoline (CAS 855760-37-1)
- 2-Chloro-4-isopropylphenol (CAS 51202-00-7)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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