5-Chloro-2,4-difluorophenylboronic Acid CAS 911645-24-4
| CAS No. | 911645-24-4 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Chloro-2,4-difluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Chloro-2,4-difluorophenylboronic Acid (CAS 911645-24-4) is a high-purity analytical reference standard with the molecular formula C6H4BClF2O2 and a molecular weight of 192.36 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-Chloro-2,4-difluorophenylboronic Acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5)
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- (3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
Recommended Standards
- 5-Chloro-2,3-difluorophenylboronic acid (CAS 2377610-07-4)
- Propofol Impurity 23 (CAS CATO-C4X-147323)
- 4-Chloro-3,5-difluorophenylboronic Acid (CAS 864759-63-7)
- (2-Isopropylphenyl)trimethylsilane (CAS 110271-39-1)
- 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine 1-oxide (CAS 146-92-9)
- 1-(3,5-Dichloropyridin-2-yl)piperazine (CAS 87394-60-3)
- Ethyl 2-(4-bromo-2-nitrophenoxy)acetate (CAS 528892-33-3)
- Moxifloxacin impurity 184 (CAS CATO-C4X-1074184)
- ((1R,4S)-4-Aminocyclopent-2-en-1-yl)methanol (CAS 136522-30-0)
- 3-[6-(4-Methyl-piperazin-1-yl)-5-trifluoromethyl-pyridin-3-yl]-benzoic acid methyl ester (CAS 1311278-77-9)
- Ethyl 5-(2-bromo-5-fluorophenoxy)pentanoate (CAS 1443354-04-8)
- 1-(3-Methylbenzyl)-1H-pyrazol-4-amine hydrochloride (CAS 1185384-91-1)
- 5-Hydroxy-2-methylbenzoxazole (CAS 23997-94-6)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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