Betamethasone Valerate EP Impurity I CAS 2802-10-0
| CAS No. | 2802-10-0 |
| Molecular Formula | C26H35FO6 |
| Molecular Weight | 462.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Betamethasone Valerate EP Impurity I is closely related to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Betamethasone Valerate EP Impurity I (CAS 2802-10-0), a pharmacopoeial impurity reference standard (molecular formula C26H35FO6, MW 462.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Betamethasone Valerate EP Impurity I (C26H35FO6) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 462.55 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Betamethasone Valerate EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H35FO6 |
| Molecular Weight | 462.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity N25 (CAS 5534-14-5)
- Betamethasone EP Impurity D (CAS 52619-05-3)
- Betamethasone Impurity 30 (CAS 52619-21-3)
- Betamethasone 17-Propionate-d5 (CAS CATO-C4X-143735)
- Betamethasone impurity 106 (CAS 330157-03-4)
- Betamethasone Impurity 42 (CAS 25122-45-6)
- Betamethasone impurity 103 (CAS CATO-C4X-1437103)
- Betamethasone Impurity 132 (CAS CATO-C4X-1437132)
Recommended Standards
- 693823-79-9 HX4T7JEV3D AMG-076 free base UNII-HX4T7JEV3D Cyclohexanecarboxylic acid, 1-(2-((4aR,11R,11aS)-1,3,4,4a,5,6,11,11a-octahydro-11-methyl-9-(trifluoromethyl)-2H-pyrido(4,3-b)carbazol-2-yl)ethyl)- (CAS 693823-79-9)
- Varenicline Impurity 64 (CAS CATO-C4X-196264)
- Triamcinolone Acetonide RC 3 (CAS 3924-70-7)
- Trilaciclib Impurity 16 (CAS CATO-C4X-304416)
- Propafenone EP Impurity D (CAS 91401-73-9)
- Enzalutamide Impurity 30 (CAS 112704-79-7)
- Pioglitazone Impurity 6 (CAS 144809-28-9)
- 2-Ethoxy-1-naphthohydrazide (CAS 869947-31-9)
- 2-{[5-(4-tert-butylphenyl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (CAS 893726-82-4)
- 2-hydroxycyclopentanecarboxylic acid (CAS 81887-89-0)
- 2-Chloro-N-[4-(pyridin-4-ylmethyl)phenyl]acetamide hydrochloride (CAS 1211497-06-1)
- Tranexamic Impurity 29 (CAS CATO-C4X-177129)
- 3-Fluoro-5-(trifluoromethoxy)benzamide (CAS 1352999-12-2)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
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