Rebamipide impurity 04 CAS 23974-11-0
| CAS No. | 23974-11-0 |
| Molecular Formula | C10H7Br2NO |
| Molecular Weight | 316.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rebamipide impurity 04 (CAS 23974-11-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H7Br2NO and a molecular weight of 316.98 g/mol.
Based on its molecular formula C10H7Br2NO, Rebamipide impurity 04 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rebamipide impurity 04 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7Br2NO |
| Molecular Weight | 316.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Rebamipide Standards
- Rebamipide Impurity 34 (CAS CATO-C4X-152334)
- Rebamipide Impurity 38 (CAS 23976-54-7)
- Rebamipide Impurity 53 (CAS CATO-C4X-152353)
- Rebamipide impurity 02 (CAS 1984832-92-9)
- Rebamipide Impurity 62 (CAS 889573-80-2)
- Rebamipide Impurity 4 (CAS 100342-53-8)
- Rebamipide impurity 22 (CAS 212502-72-2)
- Rebamipide impurity 24 (CAS CATO-C4X-152324)
Recommended Standards
- 3,6-Dibromo-8-methoxyquinoline (CAS 2121598-73-8)
- 4-(Bromomethyl)-2-(3-bromophenyl)oxazole (CAS 886363-25-3)
- 3,6-Dibromo-1-methylquinolin-2(1H)-one (CAS 954416-51-4)
- 5-(3,5-Dibromo-4-methylphenyl)oxazole (CAS 2364584-81-4)
- Topiroxostat impurity 69 (CAS CATO-C4X-105569)
- Efavirenz Impurity 6 (CAS 1627575-36-3)
- Nebivolol Hydrochloride EP Impurity A (CAS 1696472-15-7)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 383137-92-6)
- tert-Butyl 7-(hydroxymethyl)hexahydro-1H-pyrido[1,2-a]pyrazine-2(6H)-carboxylate (CAS 1824460-58-3)
- Methyl 3-chloroisoquinoline-8-carboxylate (CAS 1432514-94-7)
- 2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-5-methoxybenzonitrile (CAS 2096995-33-2)
- 1-(2-Bromoethoxy)-3-ethoxybenzene (CAS 26690-39-1)
- 2-(benZylsulfanyl)benzenecarboxylic acid (CAS 1531-80-2)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
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