Rebamipide Impurity 62 CAS 889573-80-2
| CAS No. | 889573-80-2 |
| Molecular Formula | C12H11BrN2O3 |
| Molecular Weight | 311.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rebamipide Impurity 62 (C12H11BrN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Rebamipide Impurity 62 (CAS 889573-80-2, C12H11BrN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rebamipide Impurity 62 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11BrN2O3 |
| Molecular Weight | 311.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Rebamipide Standards
- Rebamipide impurity 04 (CAS 23974-11-0)
- Rebamipide Impurity 34 (CAS CATO-C4X-152334)
- Rebamipide Impurity 38 (CAS 23976-54-7)
- Rebamipide Impurity 53 (CAS CATO-C4X-152353)
- Rebamipide impurity 02 (CAS 1984832-92-9)
- Rebamipide impurity 22 (CAS 212502-72-2)
- Rebamipide Impurity 48 (CAS CATO-C4X-152348)
- Rebamipide Impurity 4 (CAS 100342-53-8)
Recommended Standards
- methyl 5-[(4-bromophenoxy)methyl]-2-furoate (CAS 402771-33-9)
- Aprocitentan Impurity 9 (CAS CATO-C4X-33559)
- Methyl 5-((2-bromophenoxy)methyl)furan-2-carboxylate (CAS 364744-54-7)
- (2-((Benzyloxy)carbonyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)boronic acid (CAS 1020173-39-0)
- Solriamfetol Impurity 15 (CAS CATO-C4X-256315)
- Ibrutinib Impurity 90 (CAS 2417548-81-1)
- Loratadine Impurity 19 (CAS CATO-C4X-142619)
- Dotinurad Impurity 20 (CAS CATO-C4X-249420)
- tert-Butyldiphenylsilan (S-methylsulfonimidoyl)methane (CAS 1069070-10-5)
- n-Methyl-N-(2,2,2-trifluoroethyl)piperidin-4-amine hydrochloride (CAS 1432678-56-2)
- 3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride (CAS 1188265-60-2)
- tert-Butyl (2S,4R)-4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 2613300-14-2)
- (9H-Fluoren-9-yl)methyl (cyanomethyl)carbamate (CAS 117087-82-8)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
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