Apixaban Impurity 92 CAS 2403-63-6
| CAS No. | 2403-63-6 |
| Molecular Formula | C6H12ClNO |
| Molecular Weight | 149.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Apixaban Impurity 92 (CAS 2403-63-6), a pharmacopoeial impurity reference standard (molecular formula C6H12ClNO, MW 149.62 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apixaban Impurity 92 (C6H12ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H12ClNO |
| Molecular Weight | 149.62 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Apixaban Standards
- Apixaban Impurity 182 (CAS CATO-C4X-1088182)
- Apixaban Impurity 85 (CAS 14273-86-0)
- Apixaban Impurity 38 (CAS CATO-C4X-108838)
- Apixaban Impurity 96 (CAS 3471-32-7)
- Apixaban Impurity 21 (CAS 1119-46-6)
- Apixaban Impurity 104 (CAS 5819-34-1)
- Apixaban Impurity 67 (CAS 2323-81-1)
- Apixaban Impurity N2 (CAS 940-11-4)
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- Peramivir Impurity 96 (CAS CATO-C4X-183396)
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