Apixaban Impurity 85 CAS 14273-86-0
| CAS No. | 14273-86-0 |
| Molecular Formula | C6H11ClO2 |
| Molecular Weight | 150.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Apixaban Impurity 85 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Apixaban Impurity 85 (CAS 14273-86-0), a pharmacopoeial impurity reference standard (molecular formula C6H11ClO2, MW 150.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Apixaban Impurity 85 (C6H11ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H11ClO2 |
| Molecular Weight | 150.60 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
Related Apixaban Standards
- Apixaban Impurity 182 (CAS CATO-C4X-1088182)
- Apixaban Impurity 92 (CAS 2403-63-6)
- Apixaban Impurity 38 (CAS CATO-C4X-108838)
- Apixaban Impurity 96 (CAS 3471-32-7)
- Apixaban Impurity 21 (CAS 1119-46-6)
- Apixaban Impurity 67 (CAS 2323-81-1)
- Apixaban Impurity 104 (CAS 5819-34-1)
- Apixaban Impurity N2 (CAS 940-11-4)
Recommended Standards
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- Salbutamol EP Impurity F(Trifluoroacetic Acid) (CAS CATO-C4X-117650)
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- Pyruvic Acid- (CAS 905440-74-6)
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- 4-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione (CAS 338772-96-6)
- Liraglutide (CAS 204656-20-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com