5-Oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide CAS 241127-06-0
| CAS No. | 241127-06-0 |
| Molecular Formula | C22H12F6N2O3 |
| Molecular Weight | 466.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241127-06-0) is a high-purity analytical reference standard with the molecular formula C22H12F6N2O3 and a molecular weight of 466.33 g/mol.
Based on its molecular formula C22H12F6N2O3, 5-Oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 466.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-Oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H12F6N2O3 |
| Molecular Weight | 466.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Oxo Standards
- 3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 478260-60-5)
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- 1-((3,5-Bis(trifluoromethyl)phenyl)sulfonyl)-4-(2,6-dimethylphenyl)piperazine (CAS 873679-81-3)
- 2,2'-(2,5-Bis(trifluoromethyl)-1,4-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1073339-16-8)
- 1,2-Bis(trifluoromethyl)-4,5-diiodobenzene (CAS 1805519-29-2)
- 3-(Trifluoromethyl)phenyl 3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate (CAS 478260-61-6)
- N1-[2-(trifluoromethyl)phenyl]-2-({5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-4-methyl-4H-1,2,4-triazol-3-yl}thio)acetamide (CAS 650592-14-6)
- 2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-[4-(trifluoromethoxy)phenyl]acetonitrile (CAS 677749-56-3)
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- 3-(3-Methoxyphenyl)-2,2-dimethylpropan-1-amine (CAS 1266742-75-9)
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- Pazopanib Impurity 63 (CAS 2369664-23-1)
- 2-(Difluoromethyl)-5-hydroxypyridine-4-carbonyl chloride (CAS 1805307-02-1)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1116104-19-8)
- N-(2-Hydroxy-5-methylphenyl)-3-phenylpropanamide (CAS 393121-74-9)
- 3-Chloro-6-methyl-2-nitro-benzoic acid (CAS 1807146-11-7)
- (5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)methanamine (CAS 944906-80-3)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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