N-(2,4-difluorophenyl)-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide CAS 241127-07-1
| CAS No. | 241127-07-1 |
| Molecular Formula | C20H9F5N2O3 |
| Molecular Weight | 420.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,4-difluorophenyl)-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide.
N-(2,4-difluorophenyl)-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241127-07-1) is a high-purity analytical reference standard with the molecular formula C20H9F5N2O3 and a molecular weight of 420.29 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-(2,4-difluorophenyl)-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 420.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H9F5N2O3 |
| Molecular Weight | 420.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 7-[(E)-2-[(2,5-Difluorophenyl)methylidene]hydrazin-1-yl]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 338962-14-4)
- 1-(3,5-Difluorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796893-17-8)
- 2,4,6-Tris(3,4-difluorophenyl)-1,3,5,2,4,6-trioxatriborinane (CAS 1456935-98-0)
- 2,4,6-Tris(3,5-difluorophenyl)-1,3,5,2,4,6-trioxatriborinane (CAS 218963-15-6)
- 1-(2,4-Difluorophenyl)-6,8-difluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 105859-17-4)
- N-(2,4-difluorophenyl)-2-((4-fluoro-N-(pyridin-2-yl)phenyl)sulfonamido)acetamide (CAS 337922-80-2)
- 5-((1-((2,6-Difluorophenyl)sulfonyl)piperidin-3-yl)methyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole (CAS 1706106-28-6)
- 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone (CAS 471903-60-3)
Recommended Standards
- Ethyl 2,2-bis(2,4-dinitrophenyl)acetate (CAS 5833-18-1)
- N-(3,5-Dichlorophenyl)-2,4-diphenylpyrimidine-5-carboxamide (CAS 321433-23-2)
- Ethyl 2-(5-{bis[(2-chlorophenyl)methyl]amino}-2H-1,2,3,4-tetrazol-2-yl)acetate (CAS 338750-85-9)
- Diazoxide Impurity 12 (CAS CATO-C4X-195212)
- (S)-2-(3-((1R,2R)-2-Aminocyclohexyl)thioureido)-N-benzyl-N,3,3-trimethylbutanamide (CAS 479423-21-7)
- P469P1DDC0 5103-42-4 Hydrindantin (2,2'-Biindan)-1,1',3,3'-tetrone, 2,2'-dihydroxy- (8CI) (2,2'-Bi-1H-indene)-1,1',3,3'(2H,2'H)-tetrone, 2,2'-dihydroxy- 2,2'-Dihydroxy-2,2'-biindan-1,1',3,3'-tetraone 2,2'-Dihydroxy-(2,2'-biindan)-1,1',3,3'-tetrone EINECS 225-823-4 NSC 83617 UNII-P469P1DDC0 (CAS 5103-42-4)
- 3-(4-Chlorophenyl)-2',3'-dichloropropiophenone (CAS 898788-39-1)
- 176690-89-4 (2E)-3-(4-tert-Butylphenyl)prop-2-enoyl chloride DTXSID70578226 (CAS 176690-89-4)
- Thioaildenafil (CAS 856190-47-1)
- 4-Phenyl-1,2-oxazol-5-amine (CAS 4320-83-6)
- 2-(Dimethylamino)-5-(trifluoromethyl)benzonitrile (CAS 1094407-51-8)
- 5-(Thiophen-2-ylthio)thiophene-2-sulfonamide (CAS 63033-64-7)
- 3-Amino-1-methyl-4,5-dihydro-1h-pyrazol-5-one (CAS 54235-29-9)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com