3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide CAS 478260-60-5
| CAS No. | 478260-60-5 |
| Molecular Formula | C22H12F6N2OS |
| Molecular Weight | 466.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 478260-60-5), molecular formula C22H12F6N2OS and molecular weight 466.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide (C22H12F6N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Phenyl-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)thieno[3,2-b]pyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H12F6N2OS |
| Molecular Weight | 466.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Phenyl Standards
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- 5-Oxo-2-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241127-06-0)
- 2,2'-(2,5-Bis(trifluoromethyl)-1,4-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1073339-16-8)
- 1,2-Bis(trifluoromethyl)-4,5-diiodobenzene (CAS 1805519-29-2)
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Recommended Standards
- 2-((((Z)-1-(2-Aminothiazol-4-yl)-2-(((2S,3S)-2-((carbamoyloxy)methyl)-4-oxo-1-sulfoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)acetic acid (CAS 87638-04-8)
- Dnp-Pro-Gln-Gly-OH (CAS 65080-33-3)
- Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid (CAS 1446282-17-2)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 477866-74-3)
- 4-Benzyltetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 1707358-42-6)
- 2-tert-Amylphenol (CAS 3279-27-4)
- (R)-1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)pyrrolidin-3-ol (CAS 1354019-51-4)
- trans-3'-Hydroxy Cotinine Acetate (CAS 111034-55-0)
- 4-(5-Chloro-1-ethyl-1H-benzo[d]imidazol-2-yl)butanoic acid (CAS 1183451-68-4)
- (E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate (CAS 2413446-67-8)
- 6-Iodo-3,4-dihydro-2H-pyrano-[3,2-b]pyridine-8-carboxylic acid (CAS 1346447-29-7)
- 4-chloro-6-(propan-2-yl)thieno[3,2-d]pyrimidine (CAS 2306271-71-4)
- 7-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1094260-88-4)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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