8-Bromo-7-fluoro-1,5-naphthyridin-2-yl trifluoromethanesulfonate CAS 2419129-89-6
| CAS No. | 2419129-89-6 |
| Molecular Formula | C9H3BrF4N2O3S |
| Molecular Weight | 375.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Bromo-7-fluoro-1,5-naphthyridin-2-yl trifluoromethanesulfonate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-Bromo-7-fluoro-1,5-naphthyridin-2-yl trifluoromethanesulfonate (CAS 2419129-89-6), molecular formula C9H3BrF4N2O3S and molecular weight 375.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Bromo-7-fluoro-1,5-naphthyridin-2-yl trifluoromethanesulfonate (C9H3BrF4N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H3BrF4N2O3S |
| Molecular Weight | 375.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- (αE)-5-Bromo-α-[(5-bromo-2-thienyl)methylene]-2-thiopheneacetonitrile (CAS 439588-79-1)
- 4-Bromo-2,6-dichloro-N-(3-methylbutan-2-yl)benzenesulfonamide (CAS 1095871-95-6)
- 5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid (CAS 75369-60-7)
- 6-Bromo-5-fluoro-1-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-ol (CAS 1830164-33-4)
- 2-(4-(6-Bromo-2-oxo-2H-chromen-3-yl)phenoxy)acetic acid (CAS 1010877-03-8)
- 4-Bromo-N-(5-fluoro-2-nitrophenyl)benzenesulfonamide (CAS 1534688-91-9)
- (Z)-2-(5-bromo-2-fluorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 292169-72-3)
- 3-Bromo-3',3''-difluorotrityl alcohol (CAS 845790-82-1)
Recommended Standards
- Tert-butyl 3,4-dibromo-1H-indole-1-carboxylate (CAS 219943-38-1)
- TTCOOEt-Sn (CAS 2412678-09-0)
- 6,8-Dibromo-11H-indeno[1,2-b]quinoline (CAS 865658-79-3)
- 3-Cbz-6,6-dibromo-3-azabicyclo[3.1.0]hexane (CAS 681425-42-3)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-8-amine (CAS 2223046-91-9)
- Di-tert-Butyl 4,4'-Azanediylbis(methylene)bis(3-fluoro-4-methylpiperidine-1-carboxylate) (CAS 1404196-62-8)
- N-((4,4-difluoro-2,5-dimethylpiperidin-3-yl)methyl)methanesulfonamide (CAS 2366182-36-5)
- Methyl 2-(1,1-dioxidothiomorpholino)benzoate (CAS 866144-44-7)
- 3-Fluoro-4-nitrobenzyl Alcohol (CAS 503315-74-0)
- Methyl (2E)-2-(4-chlorobenzenesulfonyl)-3-(dimethylamino)prop-2-enoate (CAS 1785932-36-6)
- 6-Chloro-2,3-dimethylimidazo[1,2-b]pyridazine (CAS 17412-26-9)
- 2-((3-Benzoylphenyl)amino)-N-(isoquinolin-6-yl)acetamide (CAS 920513-37-7)
- 4-(1,3-Dimethyl-1h-pyrazol-4-yl)-2-(ethylsulfonyl)-6-(trifluoromethyl)pyrimidine (CAS 1005694-21-2)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com