5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid CAS 75369-60-7
| CAS No. | 75369-60-7 |
| Molecular Formula | C14H10BrF3N2O2 |
| Molecular Weight | 375.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid.
CATO supplies 5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid (CAS 75369-60-7), a certified reference material (molecular formula C14H10BrF3N2O2, MW 375.14 g/mol) for analytical method development and quality control.
Based on its molecular formula C14H10BrF3N2O2, 5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 375.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10BrF3N2O2 |
| Molecular Weight | 375.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-[(4-Iodoanilino)methylene]-1H-indene-1,3(2H)-dione (CAS 1020251-90-4)
- rel-1-(tert-butyl) 2-ethyl (2R,3R)-3-hydroxypiperidine-1,2-dicarboxylate (CAS 1135059-30-1)
- Ethyl 5-bromo-3-cyano-2-hydroxybenzoate (CAS 1805487-75-5)
- N4-Butyl-6-chloropyrimidine-2,4-diamine (CAS 5457-91-0)
- 3-methylcytidine Phosphoramidite (CAS CATO-C4X-288611)
- 1,1-Dimethyl-3-methylenecyclohexane (CAS 52291-22-2)
- Methyl 3-Amino-5-hydroxybenzoate (CAS 67973-80-2)
- PF-06442609 (CAS 1402002-76-9)
- Methyl 2-amino-3,3-dimethylbutanoate (CAS 3850-31-5)
- 3-Hydroxy-5-(4-methoxyphenyl)-1H,5H,6H-pyrazolo[4,3-c]pyridazin-6-one (CAS 338405-80-4)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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