3-Chloro-N-(6-(2-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide CAS 243963-22-6
| CAS No. | 243963-22-6 |
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-N-(6-(2-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Chloro-N-(6-(2-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (CAS 243963-22-6), a certified reference material (molecular formula C16H16ClFN2O2, MW 322.76 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H16ClFN2O2, 3-Chloro-N-(6-(2-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 322.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-N-(6-(2-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (3-(2-Chloro-6-fluorophenyl)-5-methylisoxazol-4-yl)(piperidin-1-yl)methanone (CAS 288317-51-1)
- 2-Chloro-N-(3-fluorophenyl)acridin-9-amine (CAS 62383-21-5)
- 3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (CAS 243963-12-4)
- 5-[(3-Chloro-1-benzothiophen-2-yl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 477868-40-9)
- N-(2-((5-Chloro-2-nitrophenyl)thio)phenyl)acetamide (CAS 107522-19-0)
- 4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-ethoxybenzoic acid (CAS 1351762-29-2)
- 3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acid (CAS 184040-74-2)
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Recommended Standards
- 2-(2-Methoxyethoxy)ethyl 2-(chlorosulfonyl)benzoate (CAS 866942-11-2)
- N1-[2-(2-fluorophenoxy)-3-pyridyl]-3-chloro-2,2-dimethylpropanamide (CAS 243963-33-9)
- N-(5-Amino-2-fluorophenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020056-16-9)
- Cycloxaprid (CAS 1203791-41-6)
- 4-(6-Methylpyridazin-3-yl)-4,5,6,7-tetrahydrothiazolo[4,5-b]pyridine-2-carboxylic acid (CAS 1422134-70-0)
- 2-Nitrophenyl 6-O-trityl-β-D-galactopyranoside (CAS 114102-89-5)
- 4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride hydrate (CAS 5549-58-6)
- 2-(4-Bromo-1h-pyrazol-1-yl)ethan-1-amine (CAS 710944-68-6)
- 2-Fluoro-6-(methoxymethoxy)benzoic acid (CAS 368422-22-4)
- 5-Bromo-1H-imidazole-4-carbaldehyde (CAS 50743-01-6)
- 6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptan-3-one (CAS 30460-92-5)
- 5-fluoroisoquinolin-3-amine (CAS 1221974-43-1)
- 1-(5-Chloro-2,4-dimethoxyphenyl)urea (CAS 196700-62-6)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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