3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide CAS 243963-12-4

Purity 97%+In StockPharmaceutical Standards
CAS No.243963-12-4
Molecular FormulaC16H16ClFN2O2
Molecular Weight322.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide CAS 243963-12-4 chemical structure

Description

3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (CAS 243963-12-4) is a high-purity analytical reference standard with the molecular formula C16H16ClFN2O2 and a molecular weight of 322.76 g/mol.

3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (C16H16ClFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H16ClFN2O2
Molecular Weight322.76 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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