| CAS No. | 243963-12-4 |
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (CAS 243963-12-4) is a high-purity analytical reference standard with the molecular formula C16H16ClFN2O2 and a molecular weight of 322.76 g/mol.
3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide (C16H16ClFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-N-(6-(4-fluorophenoxy)pyridin-3-yl)-2,2-dimethylpropanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C16H16ClFN2O2 |
| Molecular Weight | 322.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |