Bevantolol Impurity 21 CAS CATO-C4X-241121
| CAS No. | CATO-C4X-241121 |
| Molecular Formula | C20H26ClNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bevantolol Impurity 21 (C20H26ClNO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Bevantolol Impurity 21 (CAS CATO-C4X-241121, C20H26ClNO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H26ClNO3 HCl |
| Molecular Weight | 400.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bevantolol Standards
- Bevantolol Impurity 15 (CAS 14569-61-0)
- Bevantolol Impurity 5 (CAS 147220-24-4)
- Bevantolol impurity 3 (CAS 15620-78-7)
- Bevantolol impurity 1 (CAS 175157-64-9)
- Bevantolol impurity 2 (CAS 204584-12-3)
- Bevantolol hydrochloride (CAS 42864-78-8)
- Bevantolol Impurity 6 (CAS 42865-04-3)
- Bevantolol Impurity 11 (CAS 54738-08-8)
Recommended Standards
- Terbutaline impurity 111 (CAS CATO-C4X-1183111)
- Riociguat impurity 27 (CAS CATO-C4X-174927)
- Temsirolimus impurity 1 (CAS 159351-68-5)
- Ethyl 3-formyl-6-methyl-1H-indole-2-carboxylate (CAS 137076-25-6)
- Ruxolitinib Impurity 99 (CAS CATO-C4X-205899)
- 4,8-dichloro-6-fluoro-quinazoline (CAS 1566729-83-6)
- tert-Butyl ((2-oxoimidazolidin-4-yl)methyl)carbamate (CAS 2288676-96-8)
- 5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-phenyl-1H-1,2,4-triazole (CAS 400079-89-2)
- tert-Butyl ((1R,4R)-4-hydroxycyclopent-2-en-1-yl)carbamate (CAS 142633-89-4)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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