Empagliflozin impurity 215 CAS 2452301-37-8
| CAS No. | 2452301-37-8 |
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Empagliflozin impurity 215 (CAS 2452301-37-8), a pharmacopoeial impurity reference standard (molecular formula C18H17ClO4, MW 332.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H17ClO4, Empagliflozin impurity 215 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 332.78 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Empagliflozin impurity 215 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin impurity (CAS CATO-C4X-1065179)
- Empagliflozin impurity 202 (CAS CATO-C4X-1065202)
- Empagliflozin impurity 262 (CAS CATO-C4X-1065262)
- Empagliflozin Impurity 155 (CAS CATO-C4X-1065155)
- Empagliflozin impurity 207 (CAS CATO-C4X-1065207)
- Empagliflozin impurity 253 (CAS 395-11-9)
- Empagliflozin Impurity 135 (CAS 2760767-62-0)
- Empagliflozin impurity 250 (CAS CATO-C4X-1065250)
Recommended Standards
- Fenofibrate EP Impurity E (CAS 42019-07-8)
- 1,2,4-Tribromo-5-fluorobenzene (CAS 7655-70-1)
- Theophylline Impurity 6 (CAS 81781-90-0)
- 1,2,5-Tribromo-3-fluorobenzene (CAS 2839-37-4)
- Warfarin Impurity 16 (CAS CATO-C4X-142916)
- Desmopressin Impurity 28 (CAS CATO-C4X-221528)
- Daprodustat Impurity 30 (CAS CATO-C4X-240730)
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- 1-Nitro-3-(trifluoromethyl)dibenzo[b,e][1,4]dioxine (CAS 924843-88-9)
- (S)-1-(5-Fluoro-2-nitrophenyl)pyrrolidine-2-carboxylic acid (CAS 479677-28-6)
- [5-(4-Methanesulfonylphenyl)-2-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methyl 3-methylbenzoate (CAS 338749-55-6)
- 2-((1-(4-Iodophenyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid (CAS 514182-09-3)
- 4-Methyl-3,5-diphenyl-1H-pyrazol-1-yl dimethylsulfamate (CAS 400084-12-0)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
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