2-chloro-1-(4-fluorotetrahydropyran-4-yl)ethanone CAS 2452340-90-6
| CAS No. | 2452340-90-6 |
| Molecular Formula | C7H10ClFO2 |
| Molecular Weight | 180.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-chloro-1-(4-fluorotetrahydropyran-4-yl)ethanone is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-chloro-1-(4-fluorotetrahydropyran-4-yl)ethanone (CAS 2452340-90-6), molecular formula C7H10ClFO2 and molecular weight 180.60 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H10ClFO2 |
| Molecular Weight | 180.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- 2-Chloro-3,4-difluorobenzenethiol (CAS 1805223-41-9)
- 2-BROMO-5-CHLOROBENZOIC ACID 394-30-9 5-CHLORO-2-BROMOBENZOIC ACID 5-Chloro-2-fluorobenzoic acid 6-BROMO-3-CHLOROBENZOIC ACID BENZOIC ACID, 2-BROMO-5-CHLORO- LF10797 (CAS 394-30-9)
- (1R,2R)-2-fluorocyclohexyl carbonochloridate (CAS 146516-56-5)
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- 2-Bromo-1-(6-(3,4-dichlorophenyl)pyrimidin-4-yl)ethanone (CAS 1319158-63-8)
- 8-Chloro-3-phenyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 429625-88-7)
- 3,3-dimethyl-1-(piperidin-3-yl)urea hydrochloride (CAS 1909337-04-7)
- 5-Nitro-o-cresol (CAS 5428-54-6)
- Levocabastine Hydrochloride EP Impurity J (CAS CATO-C4X-228918)
- Thiazolo[5,4-d]thiazole (CAS 251-56-9)
- 4-(2,4-Dimethoxyphenyl)butan-2-ol (CAS 1341054-03-2)
- 5-Bromo-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1365889-96-8)
- Ubrogepant Impurity 1 p-Tolylcarboxylic acid (CAS 1456803-39-6)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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