Apixaban Impurity 45 CAS 24666-55-5
| CAS No. | 24666-55-5 |
| Molecular Formula | C13H14N2O4 |
| Molecular Weight | 262.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Apixaban Impurity 45 (CAS 24666-55-5, C13H14N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Apixaban Impurity 45 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Apixaban Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O4 |
| Molecular Weight | 262.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
Related Apixaban Standards
- Apixaban Impurity 178 (CAS 1579955-59-1)
- Apixaban Impurity 55 (CAS 27143-09-5/132839-05-5)
- Apixaban Impurity N1 (CAS 6947-36-0)
- Apixaban Impurity 157 (CAS CATO-C4X-1088157)
- Apixaban Impurity 99 (CAS 22715-73-7)
- Apixaban Impurity 81 (CAS CATO-C4X-108881)
- Apixaban Impurity 110 (CAS 473927-63-8)
- Apixaban Impurity 14 (CAS 405872-78-8/2228998-99-8)
Recommended Standards
- Ibrutinib Impurity 155 (CAS CATO-C4X-1064155)
- Aspartame EP Impurity A (CAS 5262-10-2)
- Ibrutinib Impurity 154 (CAS CATO-C4X-1064154)
- Cefadroxil Impurity 27 (CAS 55102-13-1)
- Pimecrolimus Impurity 11 (CAS CATO-C4X-173111)
- Fexofenadine Impurity 20 (CAS 96067-93-5)
- Thiamine /Vitamin B1 Impurity 56 (CAS 1153-39-5)
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- Ethyl 2-oxo-1-thiaspiro[4.5]decane-3-carboxylate (CAS 1822822-27-4)
- (R)-tert-Butyl (3-(1-aminoethyl)-4-fluorophenyl)carbamate (CAS 2227768-74-1)
- (1,2-Dichlorotrifluoroethyl)cyclohexane (CAS 219904-95-7)
- N-DesmethylBendamustine (CAS 41515-13-3)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com